nfkb pathway Search Results


taqman openarray rat nfkb signaling pathway panel (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
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proteome profiler human nf κb pathway array  (R&D Systems)
93
R&D Systems proteome profiler human nf κb pathway array
Effect of tumor necrosis factor-alpha (TNF-α) and MLN4924 on the signaling pathways mediating matrix metalloproteinase 9 (MMP9) gene expression in esophageal squamous cell carcinoma (ESCC) cells. ( A ) <t>Proteome</t> profiling of the nuclear factor kappa B (NFκB) pathway by antibody array analyses in the KYSE150 cells treated with MLN4924 and TNF-α. Protein lysates from the untreated controls and cells treated with MLN4924 or TNF-α alone or in combination were analyzed using a human NFκB array (R&D). ( B ) Bar graphs showing the phosphorylation ratio (upper) and the protein level ratio (bottom) calculated after the semi-quantitative analysis of selected proteins. Results are presented as means ± SEM from duplicates. * p < 0.001, ** p < 0.05 vs. controls. The complete array is shown in . ( C ) Western blot analysis showing time-dependent activation of inhibitor of nuclear factor kappa B-alpha (IκB-α), NFκB/p65 and c-Jun in the KYSE150 cells treated with TNF-α (30 ng/mL). ( D ) MLN4924-dependent changes in the activation of IκB-α, NFκB/p65 and c-Jun as well as increasing levels of cyclin dependent kinase inhibitor 1A (CDKN1a/p21) protein in the KYSE150 cells within 24 h. ( E ) A dose-dependent effect of MLN4924 on activation of NFκB/p65 and c-Jun signaling pathways in the KYSE150 cells treated with TNF-α (30 g/mL) for 24 h. The effect of the KYSE70 cells treatment with different concentrations (0.25, 0.5, 1.0, 2.5 and 5.0 µM) of MLN4924 for 24 and 48 h is shown in .
Proteome Profiler Human Nf κb Pathway Array, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nfkb+pathway/pmc07915196-190-19-25?v=R%26D+Systems
Average 93 stars, based on 1 article reviews
proteome profiler human nf κb pathway array - by Bioz Stars, 2026-08
93/100 stars
  Buy from Supplier
proteome profiler human nfkb pathway array kit  (R&D Systems)
94
R&D Systems proteome profiler human nfkb pathway array kit
Effect of tumor necrosis factor-alpha (TNF-α) and MLN4924 on the signaling pathways mediating matrix metalloproteinase 9 (MMP9) gene expression in esophageal squamous cell carcinoma (ESCC) cells. ( A ) <t>Proteome</t> profiling of the nuclear factor kappa B (NFκB) pathway by antibody array analyses in the KYSE150 cells treated with MLN4924 and TNF-α. Protein lysates from the untreated controls and cells treated with MLN4924 or TNF-α alone or in combination were analyzed using a human NFκB array (R&D). ( B ) Bar graphs showing the phosphorylation ratio (upper) and the protein level ratio (bottom) calculated after the semi-quantitative analysis of selected proteins. Results are presented as means ± SEM from duplicates. * p < 0.001, ** p < 0.05 vs. controls. The complete array is shown in . ( C ) Western blot analysis showing time-dependent activation of inhibitor of nuclear factor kappa B-alpha (IκB-α), NFκB/p65 and c-Jun in the KYSE150 cells treated with TNF-α (30 ng/mL). ( D ) MLN4924-dependent changes in the activation of IκB-α, NFκB/p65 and c-Jun as well as increasing levels of cyclin dependent kinase inhibitor 1A (CDKN1a/p21) protein in the KYSE150 cells within 24 h. ( E ) A dose-dependent effect of MLN4924 on activation of NFκB/p65 and c-Jun signaling pathways in the KYSE150 cells treated with TNF-α (30 g/mL) for 24 h. The effect of the KYSE70 cells treatment with different concentrations (0.25, 0.5, 1.0, 2.5 and 5.0 µM) of MLN4924 for 24 and 48 h is shown in .
Proteome Profiler Human Nfkb Pathway Array Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nfkb+pathway/pmc12074951-69-10-17?v=R%26D+Systems
Average 94 stars, based on 1 article reviews
proteome profiler human nfkb pathway array kit - by Bioz Stars, 2026-08
94/100 stars
  Buy from Supplier
biocarta_nfkb_pathway  (BioCarta)
90
BioCarta biocarta_nfkb_pathway
Effect of tumor necrosis factor-alpha (TNF-α) and MLN4924 on the signaling pathways mediating matrix metalloproteinase 9 (MMP9) gene expression in esophageal squamous cell carcinoma (ESCC) cells. ( A ) <t>Proteome</t> profiling of the nuclear factor kappa B (NFκB) pathway by antibody array analyses in the KYSE150 cells treated with MLN4924 and TNF-α. Protein lysates from the untreated controls and cells treated with MLN4924 or TNF-α alone or in combination were analyzed using a human NFκB array (R&D). ( B ) Bar graphs showing the phosphorylation ratio (upper) and the protein level ratio (bottom) calculated after the semi-quantitative analysis of selected proteins. Results are presented as means ± SEM from duplicates. * p < 0.001, ** p < 0.05 vs. controls. The complete array is shown in . ( C ) Western blot analysis showing time-dependent activation of inhibitor of nuclear factor kappa B-alpha (IκB-α), NFκB/p65 and c-Jun in the KYSE150 cells treated with TNF-α (30 ng/mL). ( D ) MLN4924-dependent changes in the activation of IκB-α, NFκB/p65 and c-Jun as well as increasing levels of cyclin dependent kinase inhibitor 1A (CDKN1a/p21) protein in the KYSE150 cells within 24 h. ( E ) A dose-dependent effect of MLN4924 on activation of NFκB/p65 and c-Jun signaling pathways in the KYSE150 cells treated with TNF-α (30 g/mL) for 24 h. The effect of the KYSE70 cells treatment with different concentrations (0.25, 0.5, 1.0, 2.5 and 5.0 µM) of MLN4924 for 24 and 48 h is shown in .
Biocarta Nfkb Pathway, supplied by BioCarta, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nfkb+pathway/pm38008725-173-18-2?v=BioCarta
Average 90 stars, based on 1 article reviews
biocarta_nfkb_pathway - by Bioz Stars, 2026-08
90/100 stars
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taqman array human nfkb signaling pathway 96-well plate, fast (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier
taqman openarray mouse nfkb signaling pathway panel (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier
taqman array mouse nfkb signaling pathway 384-well card (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier
taqman array human nfkb signaling pathway 96-well plate, standard (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier
nfkb pathway antibody pack  (Novus Biologicals)
N/A
The NFkB Pathway Antibody Pack from Novus is a NFkB Pathway antibody to NFkB Pathway. This antibody reacts with Human, Mouse, Rat. The NFkB Pathway antibody has been validated for the following applications: Western Blot,
   Buy from Supplier
taqman array mouse nfkb signaling pathway 96-well plate, standard (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier
taqman array rat nfkb signaling pathway 96-well plate, fast (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier
taqman openarray human nfkb signaling pathway panel (configurable)  (Thermo Fisher)
N/A
The NFkB Signaling Pathway array covers members of the Rel, NFkB, and IkB families and NFkB-responsive genes. Extracellular ligands, receptors, kinases and transcription factors responsible for pathway activation and signal propagation are also included.
   Buy from Supplier

Image Search Results


Effect of tumor necrosis factor-alpha (TNF-α) and MLN4924 on the signaling pathways mediating matrix metalloproteinase 9 (MMP9) gene expression in esophageal squamous cell carcinoma (ESCC) cells. ( A ) Proteome profiling of the nuclear factor kappa B (NFκB) pathway by antibody array analyses in the KYSE150 cells treated with MLN4924 and TNF-α. Protein lysates from the untreated controls and cells treated with MLN4924 or TNF-α alone or in combination were analyzed using a human NFκB array (R&D). ( B ) Bar graphs showing the phosphorylation ratio (upper) and the protein level ratio (bottom) calculated after the semi-quantitative analysis of selected proteins. Results are presented as means ± SEM from duplicates. * p < 0.001, ** p < 0.05 vs. controls. The complete array is shown in . ( C ) Western blot analysis showing time-dependent activation of inhibitor of nuclear factor kappa B-alpha (IκB-α), NFκB/p65 and c-Jun in the KYSE150 cells treated with TNF-α (30 ng/mL). ( D ) MLN4924-dependent changes in the activation of IκB-α, NFκB/p65 and c-Jun as well as increasing levels of cyclin dependent kinase inhibitor 1A (CDKN1a/p21) protein in the KYSE150 cells within 24 h. ( E ) A dose-dependent effect of MLN4924 on activation of NFκB/p65 and c-Jun signaling pathways in the KYSE150 cells treated with TNF-α (30 g/mL) for 24 h. The effect of the KYSE70 cells treatment with different concentrations (0.25, 0.5, 1.0, 2.5 and 5.0 µM) of MLN4924 for 24 and 48 h is shown in .

Journal: International Journal of Molecular Sciences

Article Title: The Effect of Neddylation Inhibition on Inflammation-Induced MMP9 Gene Expression in Esophageal Squamous Cell Carcinoma

doi: 10.3390/ijms22041716

Figure Lengend Snippet: Effect of tumor necrosis factor-alpha (TNF-α) and MLN4924 on the signaling pathways mediating matrix metalloproteinase 9 (MMP9) gene expression in esophageal squamous cell carcinoma (ESCC) cells. ( A ) Proteome profiling of the nuclear factor kappa B (NFκB) pathway by antibody array analyses in the KYSE150 cells treated with MLN4924 and TNF-α. Protein lysates from the untreated controls and cells treated with MLN4924 or TNF-α alone or in combination were analyzed using a human NFκB array (R&D). ( B ) Bar graphs showing the phosphorylation ratio (upper) and the protein level ratio (bottom) calculated after the semi-quantitative analysis of selected proteins. Results are presented as means ± SEM from duplicates. * p < 0.001, ** p < 0.05 vs. controls. The complete array is shown in . ( C ) Western blot analysis showing time-dependent activation of inhibitor of nuclear factor kappa B-alpha (IκB-α), NFκB/p65 and c-Jun in the KYSE150 cells treated with TNF-α (30 ng/mL). ( D ) MLN4924-dependent changes in the activation of IκB-α, NFκB/p65 and c-Jun as well as increasing levels of cyclin dependent kinase inhibitor 1A (CDKN1a/p21) protein in the KYSE150 cells within 24 h. ( E ) A dose-dependent effect of MLN4924 on activation of NFκB/p65 and c-Jun signaling pathways in the KYSE150 cells treated with TNF-α (30 g/mL) for 24 h. The effect of the KYSE70 cells treatment with different concentrations (0.25, 0.5, 1.0, 2.5 and 5.0 µM) of MLN4924 for 24 and 48 h is shown in .

Article Snippet: To determine the relative levels of 41 total and 4 serine/tyrosine phosphorylated proteins involved in NFκB signal transduction, the Proteome Profiler Human NF-κB Pathway Array (R&D Systems, ARY029) was used.

Techniques: Protein-Protein interactions, Gene Expression, Ab Array, Phospho-proteomics, Western Blot, Activation Assay